JN江南官方
学校主页
江南体育官网    
JN江南官方
学工动态
通知公告
媒体化学
学术前沿
党员之家
先锋行动
学术动态


当前位置: 江南体育官网 学术动态 正文
沈志良课题组在《Advanced Synthesis & Catalysis》上发表研究论文
阅读次数: 添加时间:2023/12/28 发布:

“On-Water” Synthesis of Sterically Congested γ-Ketophosphine Oxides Featuring a CF3- and P(O)-Tetrasubstituted Carbon Center

Man-Hang Feng,a Wen-Jun Ji,a Bo-Jie Huo,a Hao Xu,a* Mengtao Ma,b Zhi-Liang Shen,a* and Xue-Qiang Chua*

a Technical Institute of Fluorochemistry, Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, People’s Republic of China. E-mail: xuhao@njtech.edu.cn; ias_zlshen@njtech.edu.cn; xueqiangchu@njtech.edu.cn.

b Department of Chemistry and Materials Science, College of Science, Nanjing Forestry University, Nanjing 210037, People’s Republic of China.


Abstract: The distinctive hydrophobic hydration effect in the aqueous solution contributes to the success of the phospha-Michael reaction between β-CF3-β,β-disubstituted enones and diarylphosphine oxides, providing an access to biologically relevant γ-ketophosphine oxides bearing a sterically highly congested CF3- and P(O)-tetrasubstituted carbon center. More importantly, the resulting products could be further transformed into densely functionalized γ-ketophosphine oxides containing a CF3- and P(O)-tetrasubstituted carbon center.



Advanced Synthesis & Catalysis 2023, 365, 3546-3552. (Impact factor: 5.4)

论文链接:https://onlinelibrary.wiley.com/doi/abs/10.1002/adsc.202300741


地址:南京浦口区浦珠南路30号 邮编:211880 电话:025-58139535、9536、9537 邮箱:chem@njtech.edu.cn

Copyright © 2019 JN江南·体育(中国)官方网站 All Rights Reserved.

总共访问: 今日访问: